A mechanism for cell motility by active polar gels

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چکیده

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A mechanism for cell motility by active polar gels.

We analyse a generic motility model, with the motility mechanism arising by contractile stress due to the interaction of myosin and actin. A hydrodynamic active polar gel theory is used to model the cytoplasm of a cell and is combined with a Helfrich-type model to account for membrane properties. The overall model allows consideration of the motility without the necessity for local adhesion. Be...

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Motility initiation in active gels

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Spontaneous flow transition in active polar gels

– We study theoretically the effects of confinement on active polar gels such as the actin network of eukaryotic cells. Using generalized hydrodynamics equations derived for active gels, we predict, in the case of quasi one-dimensional geometry, a spontaneous flow transition from a homogeneously polarized immobile state for small thicknesses, to a perturbed flowing state for larger thicknesses....

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ژورنال

عنوان ژورنال: Journal of The Royal Society Interface

سال: 2015

ISSN: 1742-5689,1742-5662

DOI: 10.1098/rsif.2015.0161